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BPS BPS-Pharmacotherapy Exam Syllabus Topics:

BPS Pharmacotherapy (Part1 and Part2) Sample Questions:

Question 1

A new team has been established in a large healthcare system to conduct research. At the first meeting of the new team, the pharmacotherapy specialist was asked to submit a proposal for a randomized clinical study. What is the first step in formulating the research hypothesis for this proposal?

A. Determining a measurable outcome
B. Formulating an answerable question
C. Selecting an appropriate comparator
D. Selecting a viable intervention

Question 2

A study compared treatment with cinacalcet versus treatment with placebo in subjects with known hyperparathyroidism. The primary outcome of the study was the proportion of study subjects with a mean intact parathyroid hormone level < 250 pg/mL. Among the cinacalcet group (n = 371), 43% of subjects achieved the primary outcome; among the placebo group (n =
370), 5% achieved the primary outcome (p<0.05).
Which of the following is the number needed to treat (NNT)?

A. 1
B. 8
C. 14
D. 3

Question 3

A pharmacotherapy specialist is contemplating Writing a case report on a suspected penicillin induced neutropenia in a patient who received intravenous penicillin G for treatment of infective endocarditis. The specialist has established a temporal relationship between the period of medication administration and the onset of neutropenia, and has excluded other potential causes of the adverse effect.
Which of the following is the most appropriate next step in composing the case report?

A. Collect all pertinent patient information, including past medical history, laboratory data, medication history, and consent.
B. Generate ideas and wording for the patient case summary portion of the report.
C. Perform a comprehensive literature search to identify existing literature describing neutropenia in penicillin-treated patients.
D. Describe the incidence, severity, and outcome of penicillin-induced neutropenia for the introduction section of the report.

Question 4

A 40-year-old transplant recipient who is receiving cyclosporine develops seizures requiring anticonvulsant therapy. Because a drug interaction is likely to occur between cyclosporine and phenytoin, the pharmacotherapy specialist suggests that the resident do which of the following?

A. Decrease the cyclosporine dose.
B. Decrease the phenytoin dose.
C. Increase the cyclosporine dose.
D. Increase the phenytoin dose.

Question 5

In a clinical trial, when would "intention to treat" analysis be most appropriate?

A. Crossover design
B. Small sample size
C. Phase || trial
D. High drop-out rate

Solutions: